Cst smad3

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August undefined, 2024

WebHighly specific and rigorously validated in-house, Phospho-Smad2 (Ser465/467) (138D4) Rabbit Monoclonal Antibody (CST #3108) is ready to ship. ... Smad2 and Smad3 become phosphorylated at their carboxy-termini (Ser465/467 on Smad2; Ser423/425 on Smad3) by the receptor kinase TGF-β R1 (9-11). Following phosphorylation, Smad2 and Smad3 … WebMonoclonal Antibody for studying Smad3 (Ser423/Ser425) phosphate. Cited in 752 publications. Validated for WB, WB, IP, ChIP. Available in 2 sizes. …

Smad3 Antibody - Cell Signaling Technology

WebSep 27, 2024 · The antibodies used for ChIP-qPCR were anti-SMAD3 (CST and C67H9), anti-SMAD4 (CST and D3R4N), and anti-USP7(Bethyl and A300-033A). All ChIP-qPCR primers are listed in Supplementary Table S1. WebOct 2, 2024 · However, the importance of TGF-β-Smad2/3 signaling in fibroblast-mediated cardiac fibrosis has not been directly evaluated in vivo. Here, we examined pressure overload-induced cardiac fibrosis in fibroblast- and myofibroblast-specific inducible Cre-expressing mouse lines with selective deletion of the TGF-β receptors Tgfbr1/2, Smad2, … cimb swift code sarawak

Qishen granule attenuates cardiac fibrosis by regulating …

WebJul 5, 2024 · Pin1 depletion restored Smad3 protein levels and tumor-suppressive activity, suggesting that the Pin1-Smad3 interaction has a negative impact on canonical Smad3 action. Collectively, the data show that the Pin1-Smad3 interaction, facilitated by CDK-mediated Smad3 phosphorylation, is associated with oncogenic TGFβ signaling and … Web抗体：足突蛋白(podocin)、线粒体融合蛋白1(mitofusion 1，Mfn1)及Mfn2(英国Abcam公司)；线粒体分裂因子(mitochondrial fission factor，Mff)、线粒体动力蛋白(MiD49，美国Proteintech公司)；视神经萎缩症蛋白1(optic atrophy 1，OPA1,美国BD Biosciences公司)；二抗(CST公司)。 WebFeb 1, 2024 · Reciprocally, phosphorylation of SMAD3, the principal signal transducer of the TGFβ receptor, was up-regulated by over-expression of Gpr180 9. However, in the mouse liver phosphorylation of SMAD2 ... dho3 - 9155 derrington road houston tx

Phospho-Smad3 (Ser423/425) (C25A9) Rabbit mAb #9520

Smad3 Antibody Cell Signaling Technology

WebNov 30, 2024 · By contrast, the Smad3 protein level showed no significant change among the different groups (Fig. 5c). As a result, the promotion of MSC osteogenesis is mainly mediated by activation of the BMP2 ... WebJun 20, 2024 · Smad2/3 Antibody (C-8) is a mouse monoclonal IgG 2a κ, cited in 104 publications, provided at 200 µg/ml. raised against amino acids 1-425 representing full length Smad3 of human origin. Anti-Smad2/3 Antibody (C-8) is recommended for detection of Smad2 and Smad3 of mouse, rat and human origin by WB, IP, IF, IHC (P) … cimb thai loginWebNational Center for Biotechnology Information dho5 location

"WebGenetic locus: SMAD3 (human) mapping to 15q22.33; Smad3 (mouse) mapping to 9 C. SOURCE p-Smad3 (1D9) is a mouse monoclonal antibody raised against Ser 425 phosphorylated Smad3 of human origin. PRODUCT Each vial contains 100 µg IgG in 1.0 ml of PBS with < 0.1% sodium azide, 0.1% gelatin, 1% glycerol and < 0.1% stabilizer … " - Cst smad3

Cst smad3

WebPhospho-Smad2 (Ser465/467)/Smad3 (Ser423/425) (D27F4) Rabbit mAb (PE Conjugate) 11979S 美国Cell Signaling Technology(CST) 100μl TGF-beta/Smad Signaling Monoclonal Antibody 4C Phospho-BACH1/BRIP1 (Thr1133) Antibody 11983S 美国Cell Signaling Technology(CST) 100μl Cell Cycle / Checkpoint Polyclonal Antibody -20C Web960化工网为您提供TGF-β Antibody产品详细说明，厂家联系电话，及其相关产品，找TGF-β Antibody，请联系美国CST中国，，电话： 021-58356288 上960化工网，全国免费电话4000-025-960

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Web购买我公司生化试剂质量保证，价格实惠。872-50-4 1-甲基-2-吡咯烷酮一旦售出，都有我司专业技术人员全程指导操作, 公司所售产品都为近期，订购。中文名称：872-50-4 1-甲基-2-吡咯烷酮其他中文名称： n-甲基吡咯烷酮；1-甲基吡咯烷酮；n-甲基-2-吡咯烷酮；nmp溶剂；二异丙基酮；n-甲基-α-吡咯烷酮 WebMar 12, 2024 · A bleomycin-induced pulmonary fibrosis animal model used SD rats. Morphological changes were analyzed by hematoxylin-eosin staining. RT-qPCR and western blot were used for the detection of the expression of TGF-β1, collagen I, collagen III, E-cadherin, fibronectin and the ratios of p-Smad2/Smad2, p-Smad3/Smad3.

WebSep 15, 2024 · The cell lysate concentration was adjusted to 1 µg/µl. Then, we added the YAP (CST, Rabbit, Cat. No. 14074S), Smad2 (CST, Rabbit, Cat. No. 5339S), and Smad3 (CST, Rabbit, Cat. No. 9523S) primary antibodies to the cell lysate individually. And an equal amount of isotype control (CST, Cat. No. 2729S) was used as a negative control. WebSep 10, 2016 · Decreased level of AZIN1 activated TGF-β1 while down-regulation of JNK1 resulted in activation of ERK and p38 kinase leading to Smad3 activation and ultimately cardiac fibrosis. Importantly, systemic neutralization of miR-433 or adeno-associated virus 9 (AAV9)-mediated cardiac transfer of a miR-433 sponge attenuated cardiac fibrosis and ...

WebFeb 12, 2024 · RIP analysis showed that Smad3, but not Smad2/4, directly bound Crnde (Fig. 4B). Most interestingly, there was no change in the effect of Crnde on Smad3 protein and phosphorylation in TGFβ-induced myofibroblast differentiation (Fig. 4C,D). It is known that Smad3 binds to the promoter region of Acta2 to regulate the expression of α-SMA …

WebAug 14, 2024 · Smad3 directly induces Smad7 production, while Smad7 contributes to the degradation of Smad3. 14 In this study, renal IRI significantly induced the upregulation of TGF-β1 at both mRNA and protein levels during the AKI-to-CKD continuum. The increase of TGF-β1 resulted in the upregulation of p-Smad2, p-Smad3, and Smad4, as well as the ... dho5 amazon houstonWebFeb 15, 2024 · Further study has shown that SMAD3 directly binds to the promoter regions of NIT1 and enhances the transcription of NIT1. ... (1:1000 dilution; Abcam, USA), anti-p-Smad2 (1:500 dilution; CST, USA ... cimb thai online campaignWebSmad2 (L16D3) Mouse mAb detects endogenous levels of total Smad2 protein and may detect Smad3 due to high sequence homology. Species Reactivity: Human, Mouse, Rat, Monkey. ... Products sold or licensed by CST are provided for Customer as the end-user and solely for research and development uses. Any use of Product for diagnostic, … cimbthai bizchannelWebApr 10, 2024 · TGF-beta 506 transactivates EGFR and facilitates breast cancer migration and invasion through canonical Smad3 507 and ERK/Sp1 signaling pathways. ... at 4Â°C overnight. All antibodies are purchased from Cell Signaling 717 Technology (CST, Danvers, MA, USA), except the EGFR antibody cocktail (Cat 718 No. AHR5062, RRID: … cimb thai careerWebAnti-phospho Smad1/Smad5/Smad8 (Ser463/465)-Antikörper from rabbit, purified by affinity chromatography; Synonyms: Mothers against decapentaplegic homolog 1, BSP-1, hSMAD1, JV4-1, MAD homolog 1, Mothers against DPP homolog 1, Mad-related protein 1, SMAD 1, SMAD family member 1, Smad1, Transforming growth factor-beta-signaling … dho8 houston txWebFeb 11, 2024 · 松果菊苷（上海融禾医药科技发展有限公司，纯度97%，批号：190906）；兔多克隆抗体TGF-β1（美国 Abcam 公司）；phospho-Smad2（p-Smad2,美国 CST 公司）；phospho-Smad3（p-Smad3, Bioss公司）；蛋白Marker（美国Thermo 公司）；Trizol 试剂（加拿大Roche 公司）；逆转录试剂盒（谷歌 ... cimb thai researchWebJul 23, 2016 · Clones Smad2,Smad3 Smad7siRNA least90% inhibition targetgenes were chosen furtheranalysis. experimentalprocedures, second thirdpassages eachclone were used. knockdowncells monitoredduring culture under invertedmicroscope. ... were performed codedslides blindedfashion. Western blot Low-molecular weight marker (Cell Signaling … cimb thai financial statement