WebJul 7, 2016 · Haplotype phasing is a fundamental problem in medical and population genetics. Phasing is generally performed via statistical phasing within a genotyped cohort, an approach that can attain high accuracy in very large cohorts but attains lower accuracy in smaller cohorts. Here, we instead explore the paradigm of reference-based phasing. We … WebOct 21, 2024 · Abstract. We present the expression modifier score (EMS), a predicted probability that a variant has a cis-regulatory effect on gene expression, trained on fine …
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WebHilary K. Finucane focuses on Genome-wide association study, Heritability, Genetics, Computational biology and Genetic association. Her research in Genome-wide … WebJul 8, 2024 · Hilary K. Finucane & Alkes L. Price Nature Genetics 51 , 1202–1204 ( 2024) Cite this article 3089 Accesses 29 Citations 3 Altmetric Metrics To the Editor — Recent work has highlighted the... try formal word
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WebSep 28, 2015 · Finucane HK 2, Anttila V 1, Gusev A 3, Day FR 4, Loh PR 1, ReproGen Consortium, ... Brendan Bulik-Sullivan, 1, 2, 3, * Hilary K Finucane, 4, * Verneri Anttila, 1, 2, 3 Alexander Gusev, 5, 6 Felix R. Day, 7 Po-Ru Loh, 1, 5 ReproGen Consortium, 8 Psychiatric Genomics Consortium, 8 Genetic Consortium for Anorexia Nervosa of the Wellcome Trust … WebYakir A Reshef, 1, 2, 3, * Hilary K Finucane, 3 David R Kelley, 4 Alexander Gusev, 5 Dylan Kotliar, 3 Jacob C Ulirsch, 3, 5, 6 Farhad Hormozdiari, 3, 7 Joseph Nasser, 3 Luke O’Connor, 7, 8 Bryce van de Geijn, 7 Po-Ru Loh, 3, 9 Sharon R Grossman, 2, 3 Gaurav Bhatia, 7 Steven Gazal, 7 Pier Francesco Palamara, 3, 7, 10 Luca Pinello, 3, 11, 12 ... WebOct 17, 2024 · Fine-mapping aims to identify causal variants impacting complex traits. Several recent methods improve fine-mapping accuracy by prioritizing variants in enriched functional annotations. However, these methods can only use information at genome-wide significant loci (and/or a small number of functional annotations), severely limiting the … try formula dog