Mds1 and evi1 complex locus
Web22 mrt. 2024 · EVI1 is an oncogenic zinc-finger transcription factor whose overexpression contributes to disease progression and an aggressive phenotype, correlating with poor … WebLenti ORF particles, MECOM (Myc-DDK-tagged)-Human MDS1 and EVI1 complex locus (MECOM), transcript variant 1, 200ul, >10^7 TU/mL Supplier Page. Supplier Page from OriGene Technologies for EVI1 (MECOM) (NM_001105077) Human Tagged ORF Clone Lentiviral Particle. Product Specs; Company Info;
Mds1 and evi1 complex locus
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Web14 mrt. 2024 · Heterozygous mutations in MECOM (MDS1 and EVI1 complex locus) have been reported to be causative of a rare association of congenital amegakaryocytic thrombocytopenia and radioulnar synostosis. Here we report on 12 patients with congenital hypomegakaryocytic thrombocytopenia caused by MECOM mutations (including 10 … WebMDS1 and EVI1 Complex Locus Protein. MECOM encodes 2 distinct proteins, MDS1-EVI1 and EVI1 (transcription factor), via alternative splicing and distinct transcription …
WebDescription: Homo sapiens MDS1 and EVI1 complex locus (MECOM), transcript variant 4, mRNA. (from RefSeq NM_004991) RefSeq Summary (NM_004991): ...
Web5 nov. 2024 · Background: Activation of MDS1-EVI1 Complex (MECOM) via proviral insertion at its gene locus (Morishita et al., 1988) or through chromosomal rearrangements at 3q26 (Suzukawa et al., 1994; Tang et al., 2024) results in marked overexpression of EVI1, and is predominantly associated with myeloid malignancies (Secker-Walker et al., 1995), … WebMDS1 and EVI1 Complex Locus Protein. MECOM (previously known as EVI1) is inappropriately expressed in a variety of AMLs, including AML with inv(3)(q21.3;q26.2) …
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WebGeneral notes. This product is a recombinant monoclonal antibody, which offers several advantages including: - High batch-to-batch consistency and reproducibility. - Improved sensitivity and specificity. - Long-term security of supply. - Animal-free production. For more information see here. rezildaWeb7 feb. 2024 · Mecom MDS1 and EVI1 complex locus [ Mus musculus (house mouse) ] Gene ID: 14013, updated on 7-Feb-2024 Download Datasets Summary Official Symbol … rezilanWebMDS1 and EVI1 complex locus protein Curated. Myelodysplasia syndrome 1 protein; ... A chromosomal aberration involving EVI1 is a cause of chronic myelogenous leukemia (CML). Translocation t(3;21)(q26;q22) ... Evi-1c, Mds1/Evi1. Note. Produced by alternative promoter usage. rezilens logoWebThe MDS and EVI1 complex locus (MECOM) isoforms regulate their own transcription and have different roles in the transformation of hematopoietic stem and … reziliere telekom mobileWebMDS1 and EVI1 complex locus protein EVI1 (MECOM) also known as ecotropic virus integration site 1 protein homolog (EVI-1) or positive regulatory domain zinc finger … rezilinWebThe MECOM (MDS1 and EVI1 complex locus) oncogene at 3q26.2 is often rearranged in haematological malignancies of myeloid origin. MECOM encodes a zinc finger protein that is inappropriately expressed in the leukaemic cells of between 2-5% … reziliere telekom.roWeb18 dec. 2024 · The murine Evi1 gene encodes a protein that has multiple 28-amino acid repeats containing the consensus sequence found in the zinc finger domains of many … rezilienta bogdan hrib